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Structure of the chromosomal gene for human serum prealbumin

Identifieur interne : 004D88 ( Main/Exploration ); précédent : 004D87; suivant : 004D89

Structure of the chromosomal gene for human serum prealbumin

Auteurs : Sasaki Hiroyuki [Japon] ; Yoshioka Naoko [Japon] ; Takagi Yasuyuki ; Sakaki Yoshiyuki [Japon]

Source :

RBID : ISTEX:BBF9C4A70FDEBE8D4E168B9AD5C007CF452A7889

English descriptors

Abstract

Abstract: The human prealbumin gene has been cloned and its complete nucleotide sequence determined. The gene has a size of about 6.9 kb and is composed of four exons and three introns. Two Alu family sequences having opposing polarity were found in introns. In the 5'-flanking region, we found two overlapping sequences which have extensive homology to the glucocorticoid-responsive element. Three sequences identical with the enhancer core sequence were identified in introns and the 3' -flanking region. Unusual tandem repeats of a sequence, TTTTG, were also found m the 5'-flanking region and introns.

Url:
DOI: 10.1016/0378-1119(85)90272-0


Affiliations:


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Le document en format XML

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