Structure of the chromosomal gene for human serum prealbumin
Identifieur interne : 004D88 ( Main/Exploration ); précédent : 004D87; suivant : 004D89Structure of the chromosomal gene for human serum prealbumin
Auteurs : Sasaki Hiroyuki [Japon] ; Yoshioka Naoko [Japon] ; Takagi Yasuyuki ; Sakaki Yoshiyuki [Japon]Source :
- Gene [ 0378-1119 ] ; 1985.
English descriptors
- Teeft :
- Addition site, Amyloid, Amyloidotic, Biological significance, Cdna, Characteristic sequences, Chromosomal gene, Clone, Coding region, Consensus sequence, Consensus sequences, Exon, Familial amyloidotic, Family sequences, Human genome, Human prealbumin gene, Human serum prealbumin, Intron, Nucleotide, Nucleotide sequence, Polyneuropathy, Prealbumin, Prealbumin gene, Prealbumin gene expression, Putative transcription initiation site, Restriction fragments, Sasaki, Sequence analysis, Sequencing, Untranslated region.
Abstract
Abstract: The human prealbumin gene has been cloned and its complete nucleotide sequence determined. The gene has a size of about 6.9 kb and is composed of four exons and three introns. Two Alu family sequences having opposing polarity were found in introns. In the 5'-flanking region, we found two overlapping sequences which have extensive homology to the glucocorticoid-responsive element. Three sequences identical with the enhancer core sequence were identified in introns and the 3' -flanking region. Unusual tandem repeats of a sequence, TTTTG, were also found m the 5'-flanking region and introns.
Url:
DOI: 10.1016/0378-1119(85)90272-0
Affiliations:
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Le document en format XML
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<author><name sortKey="Yasuyuki, Takagi" sort="Yasuyuki, Takagi" uniqKey="Yasuyuki T" first="Takagi" last="Yasuyuki">Takagi Yasuyuki</name>
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<sourceDesc><biblStruct><analytic><title level="a">Structure of the chromosomal gene for human serum prealbumin</title>
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<author><name sortKey="Yasuyuki, Takagi" sort="Yasuyuki, Takagi" uniqKey="Yasuyuki T" first="Takagi" last="Yasuyuki">Takagi Yasuyuki</name>
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<title level="j" type="abbrev">GENE</title>
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<term>Amyloid</term>
<term>Amyloidotic</term>
<term>Biological significance</term>
<term>Cdna</term>
<term>Characteristic sequences</term>
<term>Chromosomal gene</term>
<term>Clone</term>
<term>Coding region</term>
<term>Consensus sequence</term>
<term>Consensus sequences</term>
<term>Exon</term>
<term>Familial amyloidotic</term>
<term>Family sequences</term>
<term>Human genome</term>
<term>Human prealbumin gene</term>
<term>Human serum prealbumin</term>
<term>Intron</term>
<term>Nucleotide</term>
<term>Nucleotide sequence</term>
<term>Polyneuropathy</term>
<term>Prealbumin</term>
<term>Prealbumin gene</term>
<term>Prealbumin gene expression</term>
<term>Putative transcription initiation site</term>
<term>Restriction fragments</term>
<term>Sasaki</term>
<term>Sequence analysis</term>
<term>Sequencing</term>
<term>Untranslated region</term>
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<front><div type="abstract" xml:lang="en">Abstract: The human prealbumin gene has been cloned and its complete nucleotide sequence determined. The gene has a size of about 6.9 kb and is composed of four exons and three introns. Two Alu family sequences having opposing polarity were found in introns. In the 5'-flanking region, we found two overlapping sequences which have extensive homology to the glucocorticoid-responsive element. Three sequences identical with the enhancer core sequence were identified in introns and the 3' -flanking region. Unusual tandem repeats of a sequence, TTTTG, were also found m the 5'-flanking region and introns.</div>
</front>
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<tree><noCountry><name sortKey="Yasuyuki, Takagi" sort="Yasuyuki, Takagi" uniqKey="Yasuyuki T" first="Takagi" last="Yasuyuki">Takagi Yasuyuki</name>
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<country name="Japon"><region name="Kyūshū"><name sortKey="Hiroyuki, Sasaki" sort="Hiroyuki, Sasaki" uniqKey="Hiroyuki S" first="Sasaki" last="Hiroyuki">Sasaki Hiroyuki</name>
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<name sortKey="Naoko, Yoshioka" sort="Naoko, Yoshioka" uniqKey="Naoko Y" first="Yoshioka" last="Naoko">Yoshioka Naoko</name>
<name sortKey="Yoshiyuki, Sakaki" sort="Yoshiyuki, Sakaki" uniqKey="Yoshiyuki S" first="Sakaki" last="Yoshiyuki">Sakaki Yoshiyuki</name>
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